Tilmicosin ndi pafupifupi ofanana mu zipangizo, mmene kusiyanitsa kusiyana pakati pawo?

Nkhumba ya kupuma kwa nkhumba nthawi zonse yakhala matenda ovuta omwe amavutitsa eni ake a nkhumba.Etiology ndi yovuta, tizilombo toyambitsa matenda ndi zosiyanasiyana, kufalikira kuli kwakukulu, ndipo kupewa ndi kulamulira kumakhala kovuta, zomwe zimabweretsa kuwonongeka kwakukulu kwa minda ya nkhumba.M'zaka zaposachedwa, matenda opumira a nkhumba nthawi zambiri amakhala ndi matenda osakanikirana, chifukwa chake timawatchula kuti nkhumba za nkhumba zopumira.Tizilombo toyambitsa matenda ndi Mycoplasma, Haemophilus parasuis, Actinobacillus pleuropneumoniae, khutu la buluu, circovirus ndi chimfine cha nkhumba.

Popewa komanso kuchiza matenda opuma, tilmicosin imakhala ndi zotsatira zabwino

The kupuma tizilombo toyambitsa matenda a nkhumba makamaka ogaŵikana mabakiteriya, mavairasi ndi mycoplasma.Kwa mycoplasma ndi porcine infectious pleuropneumonia, maantibayotiki omwe alipo masiku ano ayamba kukana, ndipo m'badwo watsopano wa maantibayotiki nthawi zambiri umatengedwa kuchipatala kuti ateteze ndi kuchiza matenda opumira a nkhumba.Mwachitsanzo, tilmicosin, doxycycline, tyvalomycin, etc., pamodzi ndi antiviral chikhalidwe Chinese mankhwala, ndi kwambiri zotsatira.Kafukufuku wasonyeza kuti tilmicosin ali ndi pang'ono sapha tizilombo toyambitsa matenda, ndipo ali ndi zotsatira zabwino pa ulamuliro wa porcine kupuma matenda matenda kugwirizana ndi nkhumba PRRS.

Tilmicosinali ndi ndondomeko yakuya ndipo ali ndi ubwino wambiri wophimba pawiri-wosanjikiza.

Monga tonse tikudziwa, tilmicosin ndi amodzi mwa mankhwala othandiza kwambiri polimbana ndi matenda opuma m'mafamu a nkhumba.Komabe, zotsatira za tilmicosin zosiyanasiyana pamsika ndizosafanana.Chifukwa chiyani izi?Kodi tingawasiyanitse bwanji?Nanga bwanji kusiyana kwake?Kwa tilmicosin, zopangira ndizofanana, ndipo palibe kusiyana kwakukulu.Kuwonetsa zotsatira za mankhwala, makamaka zimadalira njira yake yopangira.Popanga zinthu, kuyesetsa kuti zinthu ziziyenda bwino kwakhala kofala.kachitidwe kachitukuko.

Mapangidwe apamwambatilmicosinziyenera kukhala ndi makhalidwe anayi: nkhumba zimakonda kudya, chitetezo cha m'mimba, kusungunuka kwa matumbo ndi kutuluka pang'onopang'ono.

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Kusiyanitsa ndi maonekedwe

1. Tilmicosin particles osaphimbidwa ndi abwino kwambiri komanso osavuta kusungunuka kutentha kwa firiji, pamene tinthu tating'onoting'ono ta tilmicosin ndizovuta kwambiri kusungunuka kutentha.

2. Tilmicosin yabwino (monga Chuankexin yokutidwa ndi ma microcapsules awiri osanjikiza) imakhala ndi yunifolomu komanso yozungulira.Nthawi zambiri, tinthu tating'onoting'ono ta tilmicosin tokutidwa timasiyana kukula kwake komanso kufanana.

Siyanitsani ndi kukoma mkamwa (kukoma kwabwino)

Tilmicosinimakonda zowawa, ndipo tilmicosin yosatsekedwa si yoyenera pakamwa.Tilmicosin ndi kulawa kowawa mkamwa sikuti amangopeza ndende yamankhwala osayenera, komanso amakhudza kwambiri kudya kwa nkhumba ndikuwononga kwambiri.Kutaya mankhwala.

Siyanitsani kusungunuka kwa m'mimba ndi kusungunuka kwa enteric

1. Kupaka kwa tilmicosin kumagawidwa kukhala enteric (acid-resistant but not alkali-resistant) ndi kupaka m'mimba (osati asidi-ndi alkali-resistant).Chapamimba sungunuka (osati kugonjetsedwa ndi asidi ndi zamchere) TACHIMATA tilmicosin adzakhala kusungunuka ndi kumasulidwa ndi asidi chapamimba m'mimba, ndipo pamene mankhwala amamasulidwa, izo zitithandiza chapamimba mucosa secrete chapamimba madzi, ndipo kwambiri chapamimba madzi mosavuta chifukwa. kutuluka kwa m'mimba ndi zilonda zam'mimba.Ngati mankhwalawa asungunuka m'mimba ndikumasulidwa pasadakhale, bioavailability ya mankhwalawa idzachepetsedwa kwambiri.Nthawi zambiri, mphamvu ya mankhwala osungunuka m'mimba idzachepetsedwa ndi 10% poyerekeza ndi m'matumbo.Izi zimakulitsa kwambiri mtengo wamankhwala.

2. Kupaka kwa Enteric (anti-acid koma osati anti-alkali) Chophimbacho chikhoza kusungunuka ndi kumasulidwa kupyolera mu chilengedwe cha asidi chapamimba chosasungunuka m'malo amchere a m'matumbo, kuteteza zotsatira zosiyanasiyana ndi machitidwe a cardiotoxic omwe amayamba chifukwa cha kumasulidwa koyambirira m'mimba.Pa nthawi yomweyo, bioavailability wa mankhwala m`matumbo bwino.Kutulutsa mwachangu m'matumbo.

Kupaka kwa Enteric kumagwiritsa ntchito zida ndi njira zosiyanasiyana zokutira, komanso kutulutsa bwino m'matumbo kumasiyananso.Wamba ❖ kuyanika ndi pang`ono kusungunuka ndipo anamasulidwa m`mimba patsekeke ndi chapamimba njira, amene ndi wosiyana kwambiri ndi zotsatira za awiri wosanjikiza microcapsule ❖ kuyanika, ndi mlingo mayamwidwe mu matumbo thirakiti mofulumira.