Kuwonetsedwa ndi mankhwala ophera tizilombo, monga othamangitsa udzudzu, kumalumikizidwa ndi zotsatira zoyipa zaumoyo, malinga ndi kusanthula kwa data ya federal study.
Pakati pa anthu omwe adachita nawo kafukufuku wa National Health and Nutrition Examination Survey (NHANES), kuchuluka kwa kukhudzana ndi mankhwala ophera tizilombo omwe amagwiritsidwa ntchito kwambiri m'nyumba adalumikizidwa ndi chiwopsezo chowonjezereka cha kufa kwa matenda amtima (chiwerengero changozi 3.00, 95% CI 1.02-8.80) Dr. Wei Bao ndi anzawo aku University of Iowa ku Iowa City lipoti.
Anthu omwe ali pamtunda wapamwamba kwambiri wokhudzana ndi mankhwalawa analinso ndi 56% yowonjezera chiopsezo cha imfa kuchokera ku zifukwa zonse poyerekeza ndi anthu omwe ali otsika kwambiri omwe amakumana ndi mankhwala ophera tizilombo (RR 1.56, 95% CI 1.08-2. 26).
Komabe, olembawo adanena kuti mankhwala ophera tizilombo a pyrethroid sanagwirizane ndi imfa ya khansa (RR 0.91, 95% CI 0.31-2.72).
Zitsanzo zidasinthidwa chifukwa cha mtundu / fuko, kugonana, zaka, BMI, creatinine, zakudya, moyo, ndi chikhalidwe cha anthu.
Mankhwala ophera tizilombo a pyrethroid amavomerezedwa kuti agwiritsidwe ntchito ndi bungwe la US Environmental Protection Agency ndipo amagwiritsidwa ntchito nthawi zambiri pothamangitsa udzudzu, zothamangitsa nsabwe zapamutu, shamposi ndi zopopera za ziweto, ndi zinthu zina zoletsa tizilombo m'nyumba ndi kunja ndipo zimawonedwa ngati zotetezeka.
"Ngakhale kuti ma pyrethroids opitilira 1,000 apangidwa, pali pafupifupi 12 mankhwala ophera tizilombo pamsika waku US, monga permethrin, cypermethrin, deltamethrin ndi cyfluthrin," gulu la Bao linafotokoza, ndikuwonjezera kuti kugwiritsa ntchito pyrethroids "kwakula.""M'zaka zaposachedwa, zinthu zafika poipa kwambiri chifukwa chosiya kugwiritsa ntchito ma organophosphates m'nyumba zogona.“
Pothirira ndemanga, Stephen Stellman, Ph.D., MPH, ndi Jean Mager Stellman, Ph.D., wa payunivesite ya Columbia ku New York, ananena kuti pyrethroids “ndi mankhwala achiwiri ogwiritsiridwa ntchito kwambiri padziko lonse lapansi, okwana masauzande ambiri a mankhwala ophera tizilombo. kilogalamu ndi madola mamiliyoni mazana ambiri aku US. ”Kugulitsa kwa US ku madola aku US.“
Komanso, “mankhwala ophera tizilombo ali ponseponse ndipo kuvulazidwa kwake n’kosapeŵeka,” iwo analemba motero.Si vuto kwa ogwira ntchito m'mafamu okha: "Kupopera mbewu kwa udzudzu wa mumlengalenga kuti muchepetse kachilombo ka West Nile ndi matenda ena ofalitsidwa ndi ma vector ku New York ndi kwina kumadalira kwambiri ma pyrethroids," Stelmans akutero.
Kafukufukuyu adawunika zotsatira za anthu achikulire a 2,000 omwe adatenga nawo gawo mu projekiti ya 1999-2000 NHANES omwe adayezetsa thupi, adatenga zitsanzo za magazi, ndikuyankha mafunso a kafukufuku.Kuwonekera kwa pyrethroid kunayesedwa ndi milingo ya mkodzo ya 3-phenoxybenzoic acid, pyrethroid metabolite, ndipo otenga nawo mbali adagawidwa kukhala ma tertiles of exposure.
Pakutsata kwapakati kwa zaka 14, otenga nawo gawo 246 adamwalira: 52 kuchokera ku khansa ndi 41 kuchokera ku matenda amtima.
Pafupifupi, anthu akuda omwe sanali a ku Spain anali odziwika kwambiri ndi ma pyrethroids kuposa a Hispanics ndi azungu omwe sanali a ku Spain.Anthu omwe amapeza ndalama zochepa, maphunziro otsika, komanso zakudya zopanda thanzi amakhalanso ndi mawonekedwe apamwamba kwambiri a pyrethroid.
Stellman ndi Stellman adawunikiranso za "moyo waufupi kwambiri" wa pyrethroid biomarkers, pafupifupi maola 5.7 okha.
"Kupezeka kwa milingo yodziwika bwino ya ma metabolites a pyrethroid omwe amathetsedwa mwachangu m'magulu akulu, osiyanasiyana amawonetsa kuwonekera kwa nthawi yayitali komanso kumapangitsa kuti pakhale kofunika kuzindikira komwe kuli zachilengedwe," adatero.
Komabe, adawonanso kuti chifukwa omwe adachita nawo kafukufukuyu anali achichepere muzaka (20 mpaka 59 zaka), ndizovuta kuyerekeza kukula kwa mgwirizano ndi kufa kwamtima.
Komabe, "chiwopsezo chambiri chowopsa" chimalola kuti kufufuzidwe kowonjezereka pamankhwalawa komanso kuopsa kwawo paumoyo wa anthu, Stellman ndi Stellman adatero.
Cholepheretsa china cha phunziroli, malinga ndi olembawo, ndikugwiritsa ntchito zitsanzo za mkodzo wam'munda kuyeza ma metabolites a pyrethroid, omwe sangawonetse kusintha kwa nthawi, zomwe zimapangitsa kuti pakhale kusamvetsetsana kwachizoloŵezi cha mankhwala a pyrethroid.
Kristen Monaco ndi wolemba wamkulu yemwe amagwira ntchito pa endocrinology, psychiatry and nephrology news.Amakhala ku ofesi ya New York ndipo wakhala ndi kampaniyi kuyambira 2015.
Kafukufukuyu adathandizidwa ndi National Institutes of Health (NIH) kudzera ku University of Iowa Environmental Health Research Center.
Nthawi yotumiza: Sep-26-2023