Kafukufuku wa UI adapeza kuti pali kugwirizana pakati pa imfa za matenda a mtima ndi mitundu ina ya mankhwala ophera tizilombo.

Kafukufuku watsopano wochokera ku yunivesite ya Iowa akuwonetsa kuti anthu omwe ali ndi mankhwala enaake m'thupi mwawo, omwe akusonyeza kuti ali pachiwopsezo chachikulu chogwiritsa ntchito mankhwala ophera tizilombo, ali pachiwopsezo chachikulu chofa ndi matenda a mtima.
Zotsatira zake, zomwe zafalitsidwa mu JAMA Internal Medicine, zikusonyeza kuti anthu omwe ali ndi chiopsezo chachikulu cha matenda a mtima ndi ochepa katatu kuposa anthu omwe ali ndi chiopsezo chochepa kapena osapezeka ndi matenda a mtima.
Zotsatirazi zachokera ku kusanthula kwa chitsanzo cha akuluakulu aku US omwe akuyimira dziko lonse, osati okhawo omwe amagwira ntchito zaulimi, anatero Wei Bao, pulofesa wothandizira wa matenda a epidemiology ku University of Iowa School of Public Health komanso wolemba kafukufukuyu. Izi zikutanthauza kuti zomwe zapezekazi zili ndi zotsatira pa thanzi la anthu onse.
Anachenjezanso kuti chifukwa chakuti uwu ndi kafukufuku wowonera, sungathe kudziwa ngati anthu omwe ali mu chitsanzocho adamwalira chifukwa chokhudzidwa mwachindunji ndi tizilombo toyambitsa matenda a pyrethroids. Zotsatira zake zikusonyeza kuti pali kuthekera kwakukulu kwa kulumikizana, koma kafukufuku wowonjezereka akufunika kuti abwerezenso zotsatira zake ndikupeza njira yachilengedwe, adatero.
Mankhwala a pyrethroids ndi amodzi mwa mankhwala ophera tizilombo omwe amagwiritsidwa ntchito kwambiri pamsika, ndipo ndi ambiri mwa mankhwala ophera tizilombo a m'nyumba. Amapezeka m'mitundu yambiri ya mankhwala ophera tizilombo ndipo amagwiritsidwa ntchito kwambiri polimbana ndi tizilombo m'malo a ulimi, anthu onse komanso okhala m'nyumba. Ma metabolites a pyrethroids, monga 3-phenoxybenzoic acid, amapezeka mu mkodzo wa anthu omwe ali ndi pyrethroids.
Bao ndi gulu lake lofufuza adasanthula deta yokhudza kuchuluka kwa 3-phenoxybenzoic acid m'masampuli a mkodzo kuchokera kwa akuluakulu 2,116 azaka 20 kapena kuposerapo omwe adachita nawo kafukufuku wa National Health and Nutrition Examination Survey pakati pa 1999 ndi 2002. Adasonkhanitsa deta ya imfa kuti adziwe kuchuluka kwa akuluakulu omwe adamwalira pofika chaka cha 2015 komanso chifukwa chake.
Iwo adapeza kuti pa nthawi yotsatila ya zaka 14, pofika chaka cha 2015, anthu omwe anali ndi 3-phenoxybenzoic acid yambiri m'mkodzo anali ndi mwayi wokwana 56 peresenti womwalira chifukwa cha vuto lililonse kuposa anthu omwe anali ndi milingo yochepa kwambiri ya matendawa. Matenda a mtima, omwe ndi omwe amachititsa imfa kwambiri, ali ndi mwayi woposa katatu.
Ngakhale kuti kafukufuku wa Bao sanadziwe momwe anthu omwe adakumana ndi matenda a pyrethroid adakumana ndi matendawa, adati kafukufuku wakale wasonyeza kuti matenda ambiri a pyrethroid amapezeka kudzera mu chakudya, chifukwa anthu omwe amadya zipatso ndi ndiwo zamasamba zopopera ndi pyrethroid amadya mankhwalawo. Kugwiritsa ntchito pyrethroid polimbana ndi tizilombo m'minda ndi m'nyumba ndi gwero lofunika kwambiri la matenda. Ma pyrethroid amapezekanso mu fumbi la m'nyumba komwe mankhwala ophera tizilombowa amagwiritsidwa ntchito.
Bao adazindikira kuti gawo la msika lamankhwala ophera tizilombo otchedwa pyrethroidchawonjezeka kuyambira nthawi ya kafukufuku wa 1999-2002, zomwe zikupangitsa kuti imfa za mtima zomwe zimagwirizanitsidwa ndi kufalikira kwawo nazonso zawonjezeka. Komabe, kafukufuku wowonjezereka akufunika kuti awone ngati lingaliro ili ndi lolondola, Bao adatero.
Pepalali, “Association of exposure to pyrethroid insecticides and the risk of all-payout and cause-imfa pakati pa akuluakulu aku US,” linalembedwa ndi Buyun Liu ndi Hans-Joachim Lemler a University of Illinois School of Public Health. , pamodzi ndi Derek Simonson, wophunzira womaliza maphunziro ku University of Illinois mu human toxicology. Lofalitsidwa mu magazini ya JAMA Internal Medicine ya pa Disembala 30, 2019.