Kuphatikiza pa zomwe zapezedwa, mankhwala ophera tizilombo a organophosphate adalumikizidwa ndi kukhumudwa komanso kudzipha, kuchokera pafamu kupita kunyumba.

Phunziroli, lotchedwa "Association between Organophosphate Pesticide Exposure and Suicidal Ideation in US Adults: Population-Based Study," adasanthula zambiri zokhudzana ndi thanzi lamalingaliro ndi thupi kuchokera kwa anthu opitilira 5,000 azaka za 20 ndi kupitilira apo ku United States. Kafukufukuyu anali ndi cholinga chopereka chidziwitso chofunikira cha epidemiological paubwenzi pakati pa kuwonekera kwa mankhwala ophera tizilombo a organophosphate ndi SI. Olembawo amawona kuti kuphatikizika kwa mankhwala ophera tizilombo a organophosphate "ndikofala kwambiri kuposa kuwonekera kamodzi, koma kuwonekera kosakanikirana kumawonedwa kuti ndi kochepera ..." Kafukufukuyu adagwiritsa ntchito "njira zapamwamba zowerengera zomwe zikutuluka mu miliri ya chilengedwe kuti zithetse zowononga zambiri," olemba akupitilizabe. Mayanjano Ovuta Pakati pa Zosakaniza ndi Zotsatira Zaumoyo Zapadera" kuti awonetse mawonekedwe a mankhwala ophera tizilombo a organophosphate.
Kafukufuku wasonyeza kuti kukhudzidwa kwa nthawi yayitali kwa organophosphatemankhwala ophera tizilombokungayambitse kuchepa kwa zinthu zina zoteteza mu ubongo, kotero kuti amuna achikulire omwe ali ndi nthawi yaitali akukumana ndi mankhwala ophera tizilombo a organophosphate amakhala okhudzidwa kwambiri ndi zotsatira zovulaza za organophosphate kuposa ena. Pamodzi, zinthuzi zimapangitsa amuna achikulire kukhala pachiwopsezo chachikulu cha nkhawa, kukhumudwa, komanso zovuta zachidziwitso akakumana ndi mankhwala ophera tizilombo a organophosphate, omwe amadziwikanso kuti ndi omwe amayambitsa malingaliro ofuna kudzipha.
Organophosphates ndi gulu la mankhwala ophera tizilombo omwe amachokera ku nthawi ya Nkhondo Yachiwiri Yadziko Lonse. Ndi ma cholinesterase inhibitors, kutanthauza kuti amamangiriza mosasinthika kumalo omwe akugwira ntchito ya enzyme acetylcholinesterase (AChE), yomwe ndi yofunikira pakufalitsa kwabwino kwa mitsempha, potero kulepheretsa enzyme. Kuchepetsa kwa AChE kumalumikizidwa ndi kuchuluka kwa kupsinjika kwa anthu omwe ali pachiwopsezo chodzipha. (Onani lipoti la Beyond Pesticides apa.)
Zotsatira za kafukufuku waposachedwa zikuthandizira kafukufuku wam'mbuyomu wofalitsidwa mu WHO Bulletin, yomwe idapeza kuti anthu omwe amasunga mankhwala ophera tizilombo a organophosphate mnyumba zawo amakhala ndi malingaliro odzipha chifukwa chodziwonetsa kwambiri. Kafukufukuyu anapeza kugwirizana pakati pa maganizo ofuna kudzipha ndi kupezeka kwa mankhwala ophera tizilombo m’nyumba. M’madera amene mabanja amasunga kwambiri mankhwala ophera tizilombo, anthu ambiri amaganiza zodzipha kuposa anthu wamba. Asayansi a WHO amaona kuti mankhwala ophera tizilombo ndi imodzi mwa njira zofunika kwambiri zodzipha padziko lonse, chifukwa kuchuluka kwa mankhwala ophera tizilombo kumawapangitsa kukhala zinthu zakupha. "Organophosphate mankhwala ophera tizilombo amagwiritsidwa ntchito padziko lonse lapansi. Akamwa mowa mopitirira muyeso, amakhala mankhwala oopsa kwambiri, zomwe zimachititsa kuti anthu ambiri azidzipha padziko lonse,” anatero Dr. Robert Stewart, wofufuza wa bungwe la WHO Bulletin.
Ngakhale Beyond Pesticides yakhala ikunena za zotsatira zoyipa zamaganizidwe za mankhwala ophera tizilombo kuyambira pomwe idakhazikitsidwa, kafukufuku mderali akadali ochepa. Kafukufukuyu akuwonetsanso vuto lalikulu laumoyo wa anthu, makamaka kwa alimi, ogwira ntchito m'mafamu, ndi anthu okhala pafupi ndi mafamu. Ogwira ntchito m'mafamu, mabanja awo, ndi omwe amakhala pafupi ndi minda kapena zomera zamankhwala ali pachiwopsezo chowonekera, zomwe zimabweretsa zotsatira zoyipa. (Onani tsamba la Beyond Pesticides: Agricultural Equity and Disproportionate Risk webpage.) Kuwonjezera apo, mankhwala ophera tizilombo a organophosphate amagwiritsidwa ntchito m’madera ambiri, kuphatikizapo m’matauni, ndipo zotsalira zake zimapezeka m’zakudya ndi m’madzi, zomwe zimakhudza anthu wamba ndipo zimachititsa kuti anthu ambiri azivutika ndi organophosphate. mankhwala ndi mankhwala ena.
Ngakhale kukakamizidwa ndi asayansi ndi akatswiri azaumoyo wa anthu, mankhwala ophera tizilombo a organophosphate akupitilizabe kugwiritsidwa ntchito ku United States. Izi ndi kafukufuku wina akuwonetsa kuti alimi ndi anthu omwe ali m'madera aulimi ali pachiwopsezo chochuluka cha matenda amisala chifukwa chogwiritsa ntchito mankhwala ophera tizilombo, komanso kuti kukhudzana ndi organophosphates kumatha kubweretsa zovuta zambiri za neurodevelopmental, kubereka, kupuma, ndi zina zaumoyo. Nyuzipepala ya Beyond Pesticides-Induced Diseases (PIDD) imatsata kafukufuku waposachedwa wokhudzana ndi kupezeka kwa mankhwala ophera tizilombo. Kuti mudziwe zambiri za kuopsa kwa mankhwala ophera tizilombo, onani gawo la Depression, Kudzipha, Brain and Nerve Disorders, Endocrine Disruption, ndi Cancer patsamba la PIDD.
Kugula chakudya cha organic kumathandiza kuteteza ogwira ntchito m’mafamu ndi anthu amene amadya zipatso za ntchito yawo. Onani Kudya Mosamala kuti mudziwe za kuopsa kwa mankhwala ophera tizilombo mukamadya zipatso ndi ndiwo zamasamba wamba, komanso kuti muganizire ubwino wodya organic, ngakhale pa bajeti.