Doxycycline HCl CAS 24390-14-5 Yapamwamba Kwambiri yokhala ndi mtengo wabwino kwambiri
Mafotokozedwe Akatundu
Mwa kumangirirana mosinthika ku cholandirira chomwe chili pa 30S subunit ya ribosome ya bakiteriya, doxycyclin imasokoneza mapangidwe a ribosome complex pakati pa tRNA ndi mRNA, ndikuletsa unyolo wa peptide kuti usatalikitse kapangidwe ka mapuloteni, kotero kuti kukula ndi kuberekana kwa mabakiteriya kumalepheretsedwa mwachangu. Doxycycline imatha kuletsa mabakiteriya a gram-positive ndi gram-negative, ndipo imalimbana ndi oxytetracycline ndi aureomycin.
Akusinthidwa
Pochiza matenda opatsirana omwe amayamba chifukwa cha mabakiteriya a gramu-positive ndi gramu-negative ndi mycoplasma, monga nkhumba mycoplasma, colibacillosis, salmonellosis, pasteurellosis, ndi zina zotero.
Zotsatira zoyipa
Zotsatira zoyipa kwambiri za doxycycline hydrochloride m'kamwa mwa agalu ndi amphaka ndi kusanza, kutsegula m'mimba, komanso kuchepa kwa chilakolako cha chakudya. Pofuna kuchepetsa zotsatira zoyipa, palibe kuchepa kwakukulu kwa kuyamwa kwa mankhwala komwe kunawonedwa atamwedwa ndi chakudya. 40% ya agalu omwe akulandira chithandizo adawonetsa kuwonjezeka kwa ma enzyme okhudzana ndi ntchito ya chiwindi (alanine aminotransferase, alkaline phosphatase). Kufunika kwa ma enzyme okhudzana ndi ntchito ya chiwindi sikunadziwikebe.
